Early-career scientists show how the GLP-1 hormone affects eating

The communication about when to eat, what to eat and how much to eat is relayed to the brain through gut-brain signaling circuits. Four UF postdoctoral scholars collaborated with postdoctoral scholars from University College London and Florida State University to resolve the age-old question about how the gut and brain glucagon-like peptide-1 (GLP-1) systems interact. In a recent study published in Nature Metabolism, this team of early-career obesity scientists solved the mystery by showing that gut and brain GLP-1 systems do not interact; rather, they suppress eating via independent circuits.

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